List of seminars:


Patricia Burgos


  • Interplay between the autophagy-lysosomal pathway and the ubiquitin-proteasome system: a target for therapeutic development in Alzheimer’s disease
  • BACE1 and its amyloidogenic C99 product as mediators of organelle damage in Alzheimer’s disease


Lawrence Rajendran

  • Endo-Lyso.autophagosomal function and dysfunction in Alzheimer’s disease
  • A biphasic amyloid-synapse model integrating genetics, lifestyle and nutrition on the Alzheimer’s disease risk


Thierry Galli

  • Lysosomal and autophagosomal secretion
  • Role of autophagosomal secretion in neurite growth


Angelo Poletti

  • Motoneuron diseases and the protein quality control system.
  • The molecular regulation of the interplay between autophagy and the proteasome, as a way to protect from neurodegeneration

Tim Vervliet (Geert)

  • Ca2+ signaling in autophagy: a focus on the brain
  • Endoplasmic reticulum Ca2+ release channels as regulators of autophagy

Franck Oury

  • Systemic milieu, brain cognitive functions and aging
  • Autophagic regulation of cognitive functions and its implication during brain aging





Wim Annaert

  • Tipping the balance to autophagy or endolysosomal dysfunction in neurodegeneration: what are genetics telling to cell biologists?
  • Presenilin function in endosomes: relevance for both late and early onset Alzheimer’s disease?


David C Rubinsztein

  • Autophagy and neurodegenerative diseases (overview)
  • Autophagy and polyglutamine diseases

Patrik Verstreken

  • Synaptic autophagy defects in Parkinson’s disease
  • Genetic analyses of synaptic defects in Drosophila

Michela Matteoli

  • Microglia and synaptic pruning
  • Role of trem2 in synaptic pruning: implications for neurodevelopmental and neurodegenerative brain diseases

Francesco Cecconi

  • Selective autophagy and its role in cancer: novel and known pathways
  • Autophagy regulation in brain tumors